MST® FOLATE 400 QUATREFOLIC®: Active Folate Generation for Cellular Processes and Reduction of Tiredness
MST® Folate 400 Quatrefolic® (90 or 180 capsules) is a premium food supplement, made in Germany (MADE IN GERMANY). It contains the most advanced, bioactive form of folate: 400 µg Quatrefolic® per capsule (equivalent to 200% of the Nutrient Reference Values, NRV). If you are looking for where to buy in Germany and want to buy at the best price, this product offers a direct and effective solution. Quatrefolic® is 4th-generation folate in the form of (6S)-5-methyltetrahydrofolic acid (5-MTHF) and was developed to overcome the limitations of conventional folic acid. This product provides a form of vitamin B9 that is directly available to the body and helps support important metabolic and cellular processes.
The superiority of Quatrefolic® (5-MTHF) over conventional folic acid
Folate (vitamin B9) is an essential micronutrient. Conventional folic acid, a synthetic form, must be converted in the body into the biologically active form 5-MTHF through a multi-step process involving the MTHFR enzyme [1.2, 1.3].
Bypassing the metabolic pathway
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Bioactive form: Quatrefolic® directly provides active 5-MTHF (glucosamine salt), which is structurally identical to the form naturally found in the body [1.3].
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Full availability: By providing 5-MTHF directly, it bypasses the often inefficient conversion step by the MTHFR enzyme [1.2]. This is particularly beneficial for people with certain genetic variants (polymorphisms) that limit the conversion of folic acid to 5-MTHF [1.2, 2.5].
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High stability: Compared with earlier forms of folate, Quatrefolic® demonstrates improved stability and higher water solubility [1.3].
Legally Approved Functions of Folate (According to EU Regulation 432/2012)
The effects of folate on the body have been scientifically confirmed by the European Food Safety Authority (EFSA) and approved for use in food supplements [3.1]:
1. Cellular and Metabolic Processes
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Folate contributes to the reduction of tiredness and fatigue. This is related to its role in energy metabolism and normal blood formation [1.5, 3.6].
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Folate contributes to normal amino acid synthesis. Folate in the form of 5-MTHF is a necessary cofactor for the synthesis of nucleic acids and proteins [1.1].
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Folate contributes to normal homocysteine metabolism. 5-MTHF is crucial for the remethylation reaction, in which it converts toxic homocysteine into methionine [2.2, 2.5].
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Folate contributes to normal blood formation. Folate is necessary for the synthesis of DNA and RNA, which ensures the maturation of erythrocytes [1.1].
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Folate has a role in cell division. As a precursor of nucleic acids, folate is required for rapid cell growth and replication [1.1].
2. Specific areas of application
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Folate contributes to normal psychological function. Folate is required for the synthesis of neurotransmitters such as serotonin and dopamine, which influence mood and cognitive processes [1.5].
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Folate contributes to the normal function of the immune system. Folate is necessary for the proliferation of lymphocytes (T cells) during the immune response [1.1].
Benefits of the MST® formulation and dosage
MST® Folate 400 Quatrefolic® offers an optimally dosed, highly pure formulation:
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Critical dosage: Each capsule contains 400 µg of folate in the form of Quatrefolic® (200% NRV), which corresponds to the recommended daily dose for food supplements, particularly when requirements are increased.
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Highest bioavailability: By directly providing the active form 5-MTHF, the folate is immediately available to the body, without having to wait for enzymatic conversion [1.3].
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Premium raw material: Uses the patented, branded 4th-generation ingredient Quatrefolic® by Gnosis by Lesaffre.
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MADE IN GERMANY: Guaranteed to meet strict German quality and purity standards.
Detailed overview of ingredients and dosage (per 1 capsule – daily dose)
| Ingredient (ingredients) | Per capsule | % NRV* |
| Quatrefolic® folic acid (folic acid Quatrefolic®) | 400 µg | 200% |
*NRV = % of Nutrient Reference Values (according to Regulation (EU) No. 1169/2011)
Excipients: (According to the original packaging, e.g., filler, HPMC capsule shell, etc.)
Directions for use and notes
Recommended dosage:
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Take 1 capsule daily.
Directions for use:
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The capsule should be taken daily with sufficient water.
Important notes (EU-compliant):
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Do not exceed the recommended daily intake.
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Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle.
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Consultation with a specialist: People taking medication should consult a specialist before use.
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Storage: Keep out of reach of young children.
Where to buy MST® FOLATE 400 QUATREFOLIC®: Availability in Germany and the EU
You can purchase MST Folate 400 Quatrefolic® directly from the manufacturer. This guarantees premium quality and compliance with European standards.
If you want to buy Folate Quatrefolic® at the best price in Europe, choose the official source. The product is available in Germany, including the following major cities:
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Berlin (Berlin)
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Hamburg (Hamburg)
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Munich (Munich)
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Cologne (Cologne)
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Frankfurt am Main (Frankfurt am Main)
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Official manufacturer's website (90 capsules): Folate 400 Quatrefolic® 90 capsules
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Official manufacturer's website (180 capsules): Folate 400 Quatrefolic® 180 capsules
Conclusion
MST® Folate 400 Quatrefolic® offers an intelligent, modern approach to replenishing the body's folate stores. By using the active form 5-MTHF, the product ensures high bioavailability and efficacy, regardless of individual metabolic differences such as the MTHFR polymorphism. Given folate's proven role in reducing tiredness, supporting immune and psychological function, and normalizing homocysteine levels, MST® Folate 400 Quatrefolic® is a reliable choice for daily support of the body's functions, meeting all strict European quality and safety requirements.
Research sources
[1.1] Folate Role and Recognized EFSA claims - Quatrefolic (Quatrefolic overview and EFSA claims on cell division, amino acid synthesis, blood formation, and immune function).
[1.2] Folate VS. Folic Acid - Quatrefolic (MTHFR polymorphism and active folate form).
[1.3] About folate - Quatrefolic (5-MTHF, stability, and MTHFR bypass).
[1.5] Folate contributes to psychological function and homocysteine metabolism (Review on B vitamins and cognition).
[2.2] Molecular Biology of Methylenetetrahydrofolate Reductase (MTHFR) and Overview of Mutations/Polymorphisms - NCBI (MTHFR role in homocysteine metabolism).
[2.5] MTHFR gene: MedlinePlus Genetics (MTHFR role in homocysteine and folate processing).
[3.1] Commission Regulation (EU) No 432/2012 (List of permitted health claims).
[3.6] Folate contributes to the reduction of tiredness and fatigue (EFSA claim).








